Gene interactions and pathways from curated databases and text-mining

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CTTN — EPHB2

Text-mined interactions from Literome

Martinez-Quiles et al., Mol Cell Biol 2004 : Erk phosphorylation and a mimicking S405,418D double mutation enhanced cortactin binding and activation of N-WASP
Ayala et al., J Cell Sci 2008 (Melanoma...) : In addition, through a combination of RNA interference and a wide array of cortactin phosphorylation mutants, we were able to show that three convergent regulatory inputs based on the regulation of cortactin phosphorylation by Src-family kinases, Erk1/Erk2 and PAK are necessary for invadopodia formation and extracellular matrix degradation
Seese et al., J Neurosci 2012 (MAP Kinase Signaling System) : We propose that, in the KOs, excessive basal phosphorylation of ERK1/2 disrupts its interactions with cortactin , thereby blocking the latter protein 's use of actomyosin transport systems