Gene interactions and pathways from curated databases and text-mining

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CXCL11 — PIK3R1

Text-mined interactions from Literome

Rani et al., J Biol Chem 2002 (Fibrosarcoma) : Studies with PTEN mutants suggested that the lipid kinase activity of PI3K was essential for IFN-beta induced transcription of beta-R1
Kanda et al., Eur J Immunol 2007 : Inhibitors of PI3 K , p38 MAPK, and MEK suppressed IL-18 plus IFN-gamma induced CXCL9, CXCL10, and CXCL11 production and NF-kappaB, STAT1, and IRF-1 activities
Lin et al., J Biol Chem 2011 : Thrombin induced IL-8/CXCL8 release and IL-8/CXCL8-luciferase activity were attenuated by a PI3K inhibitor ( LY294002 ), an Akt inhibitor ( 1-L-6-hydroxymethyl-chiro-inositol-2- ( ( R ) -2-O-methyl-3-O-octadecylcarbonate ) ), and the dominant negative mutants of Rac1 ( RacN17 ) and Akt ( AktDN )
Kerr et al., Cell Signal 2013 : Interestingly, Gß? as well as PI3K activation is necessary for CXCL11 induced migration of activated T-cells