Yue et al., J Steroid Biochem Mol Biol 2003
(Breast Neoplasms...) :
In aromatase over expressing MCF-7 cells, aromatase activity was reduced by inhibitors of MAPK and PI3K suggesting the involvement of protein phosphorylation in the regulation of aromatase activity
Bouraïma-Lelong et al., Reprod Fertil Dev 2010
:
Experiments using the specific phosphatidylinositol 3-kinase (PI3-K) inhibitor LY294002 revealed that PI3-K is strongly involved in FSH induced aromatase expression in Sertoli cells from both 20- and 30-day-old rats
Su et al., J Steroid Biochem Mol Biol 2011
(Breast Neoplasms) :
Our study reveals that PI3K/Akt and MAPK inhibitors suppressed aromatase activity in MCF-7aro cells ... However, PI3K/Akt pathway inhibitors stimulated aromatase activity in T47Daro cells