Gene interactions and pathways from curated databases and text-mining

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CYP19A1 — PIK3R1

Text-mined interactions from Literome

Yue et al., J Steroid Biochem Mol Biol 2003 (Breast Neoplasms...) : In aromatase over expressing MCF-7 cells, aromatase activity was reduced by inhibitors of MAPK and PI3K suggesting the involvement of protein phosphorylation in the regulation of aromatase activity
Bouraïma-Lelong et al., Reprod Fertil Dev 2010 : Experiments using the specific phosphatidylinositol 3-kinase (PI3-K) inhibitor LY294002 revealed that PI3-K is strongly involved in FSH induced aromatase expression in Sertoli cells from both 20- and 30-day-old rats
Su et al., J Steroid Biochem Mol Biol 2011 (Breast Neoplasms) : Our study reveals that PI3K/Akt and MAPK inhibitors suppressed aromatase activity in MCF-7aro cells ... However, PI3K/Akt pathway inhibitors stimulated aromatase activity in T47Daro cells