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CA2 — DNASE2
Text-mined interactions from Literome
Nakano et al., J Biochem 1976
:
No
Mg2++Ca2+ dependent
DNase activity was detected in the preparation
Umemori et al., Apoptosis 1998
:
The purified Xenopus liver endonuclease was a neutral one and
required both
Ca2+ and Mg2+ for
DNase activity
Menzorova et al., Biokhimiia 1976
:
Ca2+-Mg2+ dependent
deoxyribonuclease ( deoxyribonucleate-5'-oligonucleotidehydrolase E. C. 3.1.4.5 )
Basnakian et al., Biochem Int 1991
(Liver Neoplasms) :
DNase activity in the
presence of
Ca2+ + Mg2+, Mg2+ alone, Mn2+ alone, or EDTA, and topoisomerase I activity were measured in nuclear extracts of diethylnitrosamine ( DEN ) -induced hepatomas, regenerating, fetal, and normal rat livers
Reynolds et al., Int J Oncol 1997
:
Apoptosis is characterized by DNA digestion mediated by either a
Ca2+/Mg2+ dependent endonuclease or the acid activated
deoxyribonuclease II (DNase II)
Baril et al., Nucleic Acids Res 1977
:
Pancreatic
DNase requires both
Ca2+ and Mg2+ for its activity as measured by formation of an activated DNA template for in vitro DNA polymerase alpha assay and by the hyperchromic shift ... When precautions are taken to avoid divalent ion contamination, pancreatic
DNase is not active in the
presence of
Ca2+ or Mg2+ alone
Nakamura et al., J Biochem 1981
:
This
DNase required both
Ca2+ and Mg2+, or Mn2+ alone for its activity and the optimum pH for activity was at 6.5-7.5
Suck et al., EMBO J 1984
:
Active site geometry and folding pattern of DNase I are quite different from staphylococcal nuclease, the only other
Ca2+ dependent
deoxyribonuclease whose structure is known at high resolution