Gene interactions and pathways from curated databases and text-mining

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DOCK5 — RAC1

Text-mined interactions from Literome

Namekata et al., Proc Natl Acad Sci U S A 2010 : BDNF induces axonal sprouting through Dock dependent Rac activation, and adult transgenic mice overexpressing Dock3 exhibit enhanced optic nerve regeneration after injury without affecting WAVE expression levels
Kulkarni et al., J Biol Chem 2011 : Multiple factors confer specific Cdc42 and Rac protein activation by dedicator of cytokinesis ( DOCK ) nucleotide exchange factors
Sanematsu et al., J Biol Chem 2013 : We found that although PDGF induced Rac activation and peripheral ruffle formation were coordinately regulated by DOCK1 and DOCK5 in MEFs, DOCK1 deficiency alone impaired dorsal ruffle formation in MEFs
Kiyokawa et al., Genes Dev 1998 : Activation of Rac1 by a Crk SH3 binding protein, DOCK180