Gene interactions and pathways from curated databases and text-mining

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DOK1 — MAPK14

Text-mined interactions from Literome

Jones et al., Curr Biol 1999 (MAP Kinase Signaling System) : Interestingly, we have found that Dok-R could attenuate EGF stimulated mitogen activated protein ( MAP ) kinase activation independently of its association with rasGAP
Di Cristofano et al., J Exp Med 2001 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : p62(dok) , a negative regulator of Ras and mitogen activated protein kinase ( MAPK ) activity, opposes leukemogenesis by p210 ( bcr-abl )
Zhao et al., Mol Cell Biol 2006 : On the other hand, Dok-1 negatively regulates PDGF induced MAPK activation by acting on Ras-GAP and at least one other Dok-1 interacting protein