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DUSP1 — IRF6

Text-mined interactions from Literome

Chen et al., J Immunol 2002 : Induction of MKP-1 by LPS was found to be extracellular signal regulated kinase dependent and involved enhanced gene expression and increased protein stability
Stawowy et al., Biochem Biophys Res Commun 2003 : Induction of MKP-1 by LPS was inhibited by the protein kinase C ( PKC ) -inhibitor calphostin C, but not by the ERK1/2-pathway inhibitor PD98059, suggesting that PKC but not ERK1/2 is required for LPS mediated MKP-1 induction in CFBs
Zhao et al., J Biol Chem 2005 (Inflammation...) : MKP-1 was rapidly induced by LPS , and its induction correlated with the dephosphorylation of these MAP kinases
Sánchez-Tilló et al., J Biol Chem 2007 (MAP Kinase Signaling System) : However, only the JNK1 isoform was phosphorylated and, as determined in single knock-out mice, was necessary for Mkp1 induction by M-CSF or LPS ... Our results demonstrate a critical role for JNK1 in the regulation of Mkp1 induction and in LPS dependent macrophage activation
Ichikawa et al., Endocrinology 2008 (Inflammation) : In contrast, LNO ( 2 ) or OA-NO ( 2 ) alone up-regulated both mRNA and protein levels of MAPK phosphatase 1 (MKP-1) and strongly augmented the LPS induced MKP-1 protein expression
Bhavsar et al., Thorax 2008 (Asthma) : MKP-1 expression induced by dexamethasone and LPS , expressed as a ratio of LPS induced expression, was reduced in severe asthma
Cho et al., Inflamm Res 2009 : In view of the potential roles of PKA and MSK for MKP-1 induction and the ability of H89 to inhibit these kinases, this study examined the effect of H89 on MKP-1 induction by LPS and the role of cyclic-AMP response element binding protein ( CREB ) in the MKP-1 induction
Casals-Casas et al., Eur J Immunol 2009 : CREB and AP-1 activation regulates MKP-1 induction by LPS or M-CSF and their kinetics correlate with macrophage activation versus proliferation
Wang et al., J Biol Chem 2009 : Both accelerated gene transcription and enhanced mRNA stability contribute to the increases in iNOS expression in LPS stimulated MKP-1 ( -/- ) macrophages
Turpeinen et al., Mediators Inflamm 2011 : Stimulation with cytokine mixture or LPS enhanced also DUSP1 expression
Zhang et al., Cardiovasc Res 2012 (Endotoxemia...) : Lipopolysaccharide (LPS) increased MKP1 expression in the myocardium in vivo and in cultured neonatal cardiomyocytes in vitro ... Inhibition of Rac1 and PAK1 by a dominant negative Rac1 adenovirus ( Ad-Rac1N17 ) and PAK1 siRNA, respectively, blocked LPS induced MKP1 expression in cardiomyocytes
Lee et al., J Cell Biochem 2013 : NaHS blocked nicotine and LPS induced activation of p38, ERK, MKP-1 , PI3K, PKC, and PKC isoenzymes, and NF-?B