Kishida et al., J Biol Chem 2001
:
Dvl and CKIepsilon activated the transcriptional activity of T cell factor ( Tcf ) synergistically ... Although the Dvl mutant that binds to Axin but not to CKIepsilon activated Tcf , it did not synergize with CKIepsilon ... Another Dvl mutant that does not bind to Axin did not activate Tcf irrespective of the presence of CKIepsilon
Zhang et al., Cell Signal 2010
:
Among these, Dishevelled ( Dvl ) is a critical regulator that releases beta-catenin from degradation and stabilizes TCF4/beta-catenin complex