Gene interactions and pathways from curated databases and text-mining

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DYT13 — EEF1A2

Text-mined interactions from Literome

Krack et al., Brain 1999 (Chorea...) : After acute levodopa challenge, high-frequency stimulation of the STN reduced diphasic mobile dystonia by 50 % and peak-dose choreic dyskinaesias by 30 % ... Acute high-frequency stimulation of the STN mimics an acute levodopa challenge, concerning both parkinsonism and dyskinaesias, and suppresses off-period dystonia
Detante et al., Adv Neurol 2004 (Dystonia...) : Assuming that the mechanism of action of STN-HFS is similar regardless of the cause of dystonia, our findings suggest that the STN is not similarly involved in off-period dystonia of IPD and others dystonias
Lyons et al., J Neurosurg 2006 (Disorders of Excessive Somnolence...) : Bilateral STN DBS increased total sleep time and reduced patient reported sleep problems and early morning dystonia for up to 24 months posttreatment