Gene interactions and pathways from curated databases and text-mining

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EDN1 — PTBP1

Text-mined interactions from Literome

Yang et al., J Exp Med 2008 : Here, we report that EDN can activate myeloid DCs by triggering the Toll-like receptor (TLR)2-myeloid differentiation factor 88 signaling pathway, thus establishing EDN as an endogenous ligand of TLR2
Olgun et al., Am J Pathol 2010 (Pregnancy Complications, Infectious...) : In previous work, we have shown that infection associated PTB is controlled in our murine model by using phospharamidon, an endothelin converting enzyme-1 inhibitor ; knocking down endothelin converting enzyme-1 mRNA ; or blocking the binding of endothelin-1 to the endothelin-A ( ET ( A ) ) receptor with either BQ-123 or with HJP-272, the 6-OH compound of our series of novel synthetic ( ET ( A ) ) receptor antagonists