Gene interactions and pathways from curated databases and text-mining

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EDN3 — RELA

Text-mined interactions from Literome

Morgan et al., Am J Respir Cell Mol Biol 2005 : MBP1 induced activation of neural nuclear factor (NF)-kappaB, from 10 min to 12 h, declining by 24 h, whereas EDN induced a short lived activation of NF-kappaB
Yuan et al., Eur J Pharmacol 2009 (Inflammation...) : Ghrelin also significantly suppressed interleukin-1beta, tumor necrosis factor-alpha, and endothelin-l mRNA expression, and inhibited NF-kappaB activation
Zheng et al., Eur J Pharmacol 2010 : NF-kappaB signaling mediates vascular smooth muscle endothelin type B receptor expression in resistance arteries