Gene interactions and pathways from curated databases and text-mining

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EGF — SREBF1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Swinnen et al., Oncogene 2000 (Carcinoma...) : EGF stimulates SREBP-1c mRNA expression and induces an increase in mature nuclear SREBP-1
Weng et al., Toxicol Appl Pharmacol 2007 (Breast Neoplasms...) : In this study, we demonstrated that the EGF induced nuclear translocation of SREBP-1 was blocked by TNQ ... Treatment of MDA-MB-231 cells with PI 3-kinase inhibitors, LY294002 and Wortmannin, inhibited the EGF induced expression of FAS and nuclear translocation of SREBP-1