Gene interactions and pathways from curated databases and text-mining

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EPO — PIK3R1

Text-mined interactions from Literome

Sui et al., Br J Haematol 2000 : Interestingly, both EPO and SCF induced activation of PI3K
Ruscher et al., J Neurosci 2002 (Hypoxia-Ischemia, Brain) : EPO activates the neuronal EPO receptor and, subsequently, JAK-2 and thereby PI3K
Genc et al., Cell Biochem Funct 2010 : These results suggest that Epo induces neural HO-1 expression through the activation of PI3K , MAPK, and Nrf2 pathways, and this may unveil a novel mechanism which mediates the cytoprotective responses elicited by Epo
Sun et al., PloS one 2013 : Our results show that baicalein induced Epo and VEGF expression in a HIF1a- and PI3K/Akt dependent manner in neurons