◀ Back to ESR1
ERAP1 — ESR1
Text-mined interactions from Literome
Chen et al., Prostate 2008
:
ERAP75 functions as a coactivator to
enhance estrogen receptor alpha transactivation in prostate stromal cells ... The
effect of
ERAP75 on
ER alpha transactivation and the expression of ER alpha target genes were determined by luciferase assay and real-time PCR, respectively ...
ERAP75 can
enhance ER alpha transactivation in a dose dependent manner and up-regulate the expression of the endogenous ER alpha target gene, stromal derived factor-1 (SDF-1), in the prostate stromal cells
Chen et al., Carcinogenesis 2009
(Prostatic Neoplasms) :
CCDC62/ERAP75 functions as a coactivator to
enhance estrogen receptor beta mediated transactivation and target gene expression in prostate cancer cells
Halachmi et al., Science 1994
:
This evidence suggests that
ERAP160 may
mediate estradiol dependent transcriptional activation by the
estrogen receptor