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ERBB2 — ITGA5
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Yoon et al., Cancer Res 2006
(Breast Neoplasms...) :
In summary, we propose a novel mechanism for ErbB2 up-regulation and Ras activation in serum depleted breast cancer cells
; integrin alpha(6)beta ( 4 )
regulates the expression of
ErbB2 and the subsequent phosphorylation of EGFR and activation of Ras
Haenssen et al., J Cell Sci 2010
(Breast Neoplasms...) :
ErbB2 requires
integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells ...
Integrin alpha5 is
required for ErbB2 mediated anoikis resistance and for optimal
ErbB2 signaling to the Mek-Erk-Bim axis as depletion of integrin alpha5 reverses anoikis resistance and Bim inhibition ...
Integrin alpha5 is
required for full activation of
ErbB2 tyrosine phosphorylation on Y877 and ErbB2 phosphorylation is associated with increased activity of Src in the absence of adhesion