◀ Back to MMP9

ERVK-6 — MMP9

Text-mined interactions from Literome

Heitzer et al., J Biol Chem 2002 : VMP3 shows proteinase activity and is inhibited by EDTA or the MMP inhibitor GM 6001, but in contrast to all known proteinases, VMP3 clearly prefers copper for activity rather than zinc
Houard et al., J Cell Biochem 2003 : However, this proteinase was not inhibited by an MMP inhibitor
Moshal et al., J Cell Mol Med 2005 (Heart Failure) : Activation of MMP-2 and -9 leads to induction of proteinase activated receptor-1 (PAR-1)
Komori et al., J Toxicol Sci 2006 : In addition, the proteolytic activity was almost completely inhibited by BS-10, a MMP inhibitor , but not by the serine proteinase inhibitors, cysteine proteinase inhibitors and aspartic proteinase inhibitors
Steenport et al., J Immunol 2009 (Chronic Disease...) : Proteinase induced MMP-9 expression was blocked in macrophages preincubated with the selective COX-2 inhibitor celecoxib or transfected with COX-2 small interfering RNA ( siRNA ) ... Likewise, proteinase induced MMP-9 was blocked in macrophages preincubated with the EP4 antagonist ONO-AE3-208 or transfected with EP4 siRNA ... Thus, proteinase induced MMP-9 expression by macrophages is dependent on the release of TNF-alpha, induction of COX-2 expression, and PGE ( 2 ) engagement of EP4
Tyagi et al., J Cell Physiol 1996 (Myocardial Infarction) : These results suggested that during ischemic cardiomyopathy, initially neutrophil proteinase activates latent myocardial MMP which can degrade ECM, which continuously degrades if not controlled by TIMP, leading to ventricular dilatation and dysfunction
DeCarlo et al., J Dent Res 1997 : In this article, we demonstrate that a proteinase isolated from the periodontopathogen Porphyromonas gingivalis can activate MMP-1, MMP-3 , and MMP-9 and can catalyze the superactivation of MMP-1 by MMP-3