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ESR1 — HDAC3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Keen et al., Breast Cancer Res Treat 2003
(Breast Neoplasms) :
A novel
histone deacetylase inhibitor, scriptaid,
enhances expression of functional
estrogen receptor alpha ( ER ) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine
Peterson et al., Mol Cell Biol 2007
(Breast Neoplasms) :
SMRT is
required for full expression of the
ERalpha target genes cyclin D1, BCL-2, and progesterone receptor but not pS2, and its depletion significantly attenuated estrogen dependent proliferation of MCF-7 cells
Karmakar et al., Mol Endocrinol 2010
(Breast Neoplasms) :
Our data link the SMRT corepressor directly with SRC family coactivators in positive regulation of ERalpha dependent gene expression and, taken with the positive correlation found for SMRT and SRC-3 in human breast tumors, suggest that
SMRT can
promote ERalpha- and SRC-3 dependent gene expression in breast cancer
Khurana et al., J Biol Chem 2011
(Breast Neoplasms) :
In contrast,
histone deacetylase 7 (HDAC7)
inhibits estrogen receptor a ( ERa ) -mediated transcription