Gene interactions and pathways from curated databases and text-mining

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FAS — PIK3R1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Chang et al., J Lipid Res 2005 : In summary, we conclude that KGF requires both PI3K and JNK signaling pathways to induce SREBP-1, which in turn induces SCD-1 and FAS expression in H292 cells
Kondo et al., Oncol Rep 2005 : Although PI 3-K inhibitors did not affect Fas expression in HL-60 cells, cellular FLICE-inhibitory protein ( c-FLIP ) levels were markedly reduced by PI 3-K inhibitor treatment
Kondo et al., Oral Oncol 2006 (Carcinoma, Squamous Cell...) : Although PI 3-K inhibitors did not affect the Fas expression of OSCC cells, cellular FLICE-inhibitory protein ( c-FLIP ) levels were markedly reduced by PI 3-K inhibitor treatment
Chiang et al., Oncol Res 2005 (Carcinoma, Hepatocellular) : FAS expression in HepG2 cells was strongly inhibited by PI3K inhibitor LY294002 and JNK inhibitor II and slightly inhibited by p38 inhibitor SB203580 and MEK inhibitor PD98059, separately
Bénéteau et al., Mol Cancer Res 2008 : Herein, we show that inhibition of the PI3K signal by edelfosine triggers a Fas mediated apoptotic signal independently of the Fas/FasL interaction
Zhang et al., Front Biosci (Elite Ed) 2011 : Taken together, the present study demonstrates that T3 potentiates the cell survival action of FSH through Src- and PI3K mediated Xiap up-regulation and decreased Fas and FasL expression
Bhatt et al., Proc Natl Acad Sci U S A 2012 (Lymphoma, B-Cell...) : We found that aerobic glycolysis and FAS occur in a PI3K dependent manner and appear to be interdependent