Gene interactions and pathways from curated databases and text-mining

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FGF1 — FGF4

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Crumley et al., Oncogene 1991 : High-affinity binding and activation of a truncated FGF receptor by both aFGF and bFGF
Yamamoto et al., J Biol Chem 2008 : PDGF-AA induced the expression of the fibroblast growth factor genes Fgf3 and -7, and PDGF-BB induced the expression of Fgf1 , -3, -7, and -10, whereas short interfering RNA for Pdgfa and Pdgfb inhibited the expression of Fgf3, -7, and -10, indicating that PDGFs regulate Fgf gene expression in SMG mesenchyme
Blagovic et al., PloS one 2011 : Then we induce FGF4 signaling in minimal chemically defined medium ( N2B27 ) and inhibit FGF signaling in fully supplemented differentiation medium with cell secreted factors to determine that the non-FGF cell secreted factors are required to promote growth of differentiating mESCs
Mori et al., PloS one 2013 (Colonic Neoplasms...) : R50E is defective in inducing ternary complex formation, cell proliferation, and cell migration, and suppresses FGF signaling induced by WT FGF1 ( a dominant negative effect ) in vitro
Jouanneau et al., Growth Factors 1995 (Carcinoma...) : Our results indicate that the expression of FGF-1 may promote tumor growth, at least in part, by inducing angiogenesis, and that the acquired ability of tumor cells to secrete FGF-1 but not FGF-4 , may result in aberrant neovascularization of the tumor
Relf et al., Cancer Res 1997 (Breast Neoplasms...) : Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor , tumor growth factor beta-1, platelet derived endothelial cell growth factor , placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
Zuber et al., J Cell Physiol 1997 : Cysteine-rich FGF receptor regulates intracellular FGF-1 and FGF-2 levels
Guillonneau et al., Growth Factors 1998 : In addition, FGF2 stimulated release of endogenous FGF1 is associated with reduced apoptosis in RPE cells ... In addition, FGF2 stimulated the production and release of phosphorylated FGF1 by RPE cells
Klingenberg et al., J Biol Chem 1998 : The aFGF ( K132E ) mutant binds to and activates fibroblast growth factor receptors equally strongly as the wild-type, but it is a poor mitogen