Gene interactions and pathways from curated databases and text-mining

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FGF2 — PLCG2

Text-mined interactions from Literome

Sa et al., Mol Cell Biochem 1999 : Basic fibroblast growth factor stimulates cytosolic phospholipase A2, phospholipase C-gamma1 and phospholipase D through distinguishable signaling mechanisms ... Upon binding to FGFR1, basic FGF stimulates cytosolic form of phospholipase A2 ( cPLA2 ), phospholipase C-gamma1 ( PLC-gamma1 ) and phospholipase D ( PLD ), the key enzymes for the production of various lipid second messengers, in a tyrosine kinase dependent manner
Kanda et al., Exp Cell Res 1999 : 4N1K inhibited tyrosine phosphorylation of focal adhesion kinase and FGF-2 stimulated tyrosine phosphorylation of phospholipase C-gamma in tube forming, but not proliferating, IBE cells
Krejci et al., Exp Cell Res 2004 : FGF2 activated phospholipase Cgamma , protein kinase B, and Erk and p38 MAP kinases
Sho et al., Endocrinology 1995 : The lack of PIA stimulation of basic fibroblast growth factor induced phospholipase-C gamma activation as well as the rise in [ Ca2+ ] i suggests that the cooperative PIA action occurs specifically on phospholipase-C beta