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FGF5 — PCSK1

Text-mined interactions from Literome

Hatch et al., Orthod Craniofac Res 2007 (Craniosynostoses) : Towards this goal we have constructed a PC-1 gene promoter/firefly luciferase reporter construct, in order to more directly investigate the regulation of PC-1 by FGF/FGFR signaling in osteoblastic and non-osteoblastic cells ... Preliminary results confirm that FGF/FGFR signaling, either via treatment with FGF2 or via expression of a Crouzon syndrome associated mutant FGFR2, induces PC-1 promoter activity in osteoblastic cells in culture
Hatch et al., J Bone Miner Res 2009 : Specifically, FGF2 was unable to induce PC-1 expression in Runx2 negative nonbone cells or in calvarial cells from Runx2-deficient mice