Gene interactions and pathways from curated databases and text-mining

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FLT3 — PIK3R1

Pathways - manually collected, often from reviews:

  • KEGG Pathways in cancer: FLT3 → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, activation)
  • KEGG Acute myeloid leukemia: FLT3 → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *