Gene interactions and pathways from curated databases and text-mining

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FOXM1 — VEGFA

Text-mined interactions from Literome

Wang et al., Cancer Res 2007 (Carcinoma...) : We also found that down-regulation of FoxM1 reduced the expression of matrix metalloproteinase-2 (MMP-2), MMP-9 and vascular endothelial growth factor , resulting in the inhibition of migration, invasion, and angiogenesis
Zhang et al., Cancer Res 2008 (Brain Neoplasms...) : FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells ... FoxM1B overexpression increased VEGF expression, whereas blockade of FoxM1 expression suppressed VEGF expression in glioma cells ... Transfection of FoxM1 into glioma cells directly activated the VEGF promoter, and inhibition of FoxM1 expression by FoxM1 siRNA suppressed VEGF promoter activation
Ahmad et al., Breast Cancer Res Treat 2010 (Breast Neoplasms...) : Moreover, down-regulation of FoxM1 inhibited the expression of many factors that are involved in the degradation of extra cellular matrix and angiogenesis such as uPA, uPAR, MMP-2, MMP-9, and vascular endothelial growth factor ( VEGF ) as well as inhibited the activity of MMP-9 and VEGF
Xue et al., Journal of translational medicine 2012 (Carcinoma, Renal Cell...) : Also, down-regulation of FoxM1 reduced expression and activity of matrix metalloproteinase-2 (MMP-2), MMP-9 and vascular endothelial growth factor ( VEGF ), resulting in the inhibition of migration, invasion, and angiogenesis