Gene interactions and pathways from curated databases and text-mining

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FYN — TYR

Text-mined interactions from Literome

Liu et al., J Biol Chem 2006 : Fyn suppressed the GAP activity of wild-type TCGAP but not the Y406F mutant of TCGAP in a phosphorylation dependent manner, suggesting that Fyn mediated Tyr-406 phosphorylation negatively regulated the TCGAP activity
Lamalice et al., J Biol Chem 2006 : Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF ... We also report that the SH2 domain containing adapter molecule Nck, but not Grb2, is recruited to VEGFR-2 in a p-Tyr1214 dependent manner and that it associates with Fyn
Wu et al., J Biol Chem 2007 : Fyn mediated phosphorylation of NR2B Tyr-1336 controls calpain mediated NR2B cleavage in neurons and heterologous systems
Hansen et al., Biochem Biophys Res Commun 1997 : PDGF induced phosphorylation of Tyr28 in the N-terminus of Fyn affects Fyn activation