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GATA3 — STAT4
Text-mined interactions from Literome
Nath et al., J Immunol 2004
(Encephalomyelitis, Autoimmune, Experimental...) :
Lovastatin
induced the expression of
GATA3 and the phosphorylation of STAT6, whereas it inhibited tyrosine phosphorylation of Janus kinase 2, tyrosine kinase 2, and
STAT4
Kaminuma et al., FEBS Lett 2004
:
Among several transcription factors putatively interacting with this region,
Stat4 , which enhanced IFN-gamma promoter activity, was
down-regulated by
GATA-3 at gene transcription level
Pykäläinen et al., J Allergy Clin Immunol 2005
(Asthma) :
The transcription factors STAT6,
GATA3 , and
STAT4 mediate the cytokine induced development of naive CD4 + T cells into either T H 1 or T H 2 type