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BMP6 — GATA4

Text-mined interactions from Literome

Lee et al., Development 2004 : Our data suggest that BMP mediated activation of this regulatory region reflects both the induction of GATA genes by BMP signals, as well as modulation of the transcriptional activity of YY1 by direct interaction of this transcription factor with BMP activated SMADs
Kobayashi et al., Cloning Stem Cells 2008 : In contrast, BMP4 induced significant upregulation of Gata6, Gata4 , and LamininB1, suggesting differentiation into the primitive endoderm, visceral endoderm, and parietal endoderm, respectively
Klaus et al., Proc Natl Acad Sci U S A 2012 (Wnt Signaling Pathway) : Using FACS enrichment of cardiac progenitors in RBPJ and RBPJ/Axin2 mutants, embryo cultures in the presence of the Bmp inhibitor Noggin, and by crossing a Bmp4 mutation into the RBPJ/Axin2 mutant background, we show that Wnt and Bmp4 signaling activate specific and nonoverlapping cardiac-specific genes in the cardiac progenitors : Nkx2-5, Isl1 and Baf60c are controlled by Wnt/ß-catenin, and Gata4 , SRF, and Mef2c are controlled by Bmp signaling