Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Herzig et al., Nature 2003 (Fatty Liver) : In response to pancreatic glucagon and adrenal cortisol, the cAMP-responsive transcription factor CREB activates gluconeogenic and fatty acid oxidation programmes by stimulating expression of the nuclear hormone receptor coactivator PGC-1 ( refs 2-5 )
Schisler et al., Proc Natl Acad Sci U S A 2005 : The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose stimulated insulin secretion in islet beta cells
Hussain et al., Mol Cell Biol 1997 : The finding that a neuronal transcription factor is involved in glucagon gene transcription may explain the presence of proglucagon in certain areas of the brain as well as in pancreatic alpha cells