Gene interactions and pathways from curated databases and text-mining

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GDF15 — PIK3R1

Text-mined interactions from Literome

Jutooru et al., Mol Carcinog 2009 (Pancreatic Neoplasms) : Induction of NAG-1 in Panc28 cells was p38-MAPK- and PI3-K dependent but Egr-1 independent, whereas induction in Panc1 cells was associated with activation of p38-MAPK, PI3-K, and p42-MAPK and was only partially Egr-1 dependent
Jie et al., Mol Cell Biochem 2012 (Ion Channel Gating) : Taken together, these findings suggest that NRG-1 activates PI3K/Akt signaling and inhibits mPTP opening, and downstream apoptotic events in cardiac myocytes subjected to oxidative stress