Gene interactions and pathways from curated databases and text-mining

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CALM2 — GNRH1

Text-mined interactions from Literome

Simpson et al., Endocr Res 1987 : Cellular calmodulin content increased in response to gonadotropin releasing hormone (GnRH) , as did the concentration of cGMP, while both responses were prevented by the administration of inhibin
Ojeda et al., Brain Res 1988 : Similarly to PGE2, the stimulatory effect of the Ca2+ ionophore A 23187 on LHRH release was not affected by inhibition of calmodulin activity ... The results indicate that : ( a ) the stimulatory effect of PGE2 on LHRH release involves mobilization of intracellular Ca2+ but not the participation of calmodulin ; ( b ) the formation of PGE2 itself is calmodulin dependent ; ( c ) PGE2 stimulates cAMP formation through a calmodulin dependent mechanism that requires translocation of intracellular ( membrane ? )
Sullivan et al., Biochem J 1985 : Effects of calmodulin and lipoxygenase inhibitors on LH ( lutropin ) - and LHRH ( luliberin ) -agonist stimulated steroidogenesis in rat Leydig cells
Waters et al., Neuroendocrinology 1998 : Calcium/calmodulin dependent protein kinase II involvement in release of gonadotropin releasing hormone