Gene interactions and pathways from curated databases and text-mining

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CSF2 — GRAP2

Text-mined interactions from Literome

Bozinovski et al., J Biol Chem 2002 (MAP Kinase Signaling System) : LPS markedly activated Akt and Erk1/2, but not p38 , in a GM-CSF dependent manner in direct temporal association with NFkappaB and AP-1 activation
Senokuchi et al., J Biol Chem 2005 : GM-CSF induced p38 MAPK phosphorylation was also inhibited by farnesyl transferase inhibitor or geranylgeranyl transferase inhibitor, and farnesyl pyrophosphate and geranylgeranyl pyrophosphate prevented the suppression of GM-CSF induced p38 MAPK phosphorylation by statins
Scicchitano et al., Blood Cells Mol Dis 2008 (MAP Kinase Signaling System) : In addition, these results suggest that IL-6, IL-11, GM-CSF , G-CSF and Activin A are similarly regulated by p38 and NF-kappaB and that the MEK1, JNK and PKC pathways appear to play a more limited role in modulating cytokine expression in HBMSC
Souza-Fonseca-Guimaraes et al., J Biol Chem 2013 (MAP Kinase Signaling System) : IFN-? and GM-CSF production requires NF-?B and STAT3 activation as well as Erk dependent mechanisms for IFN-? and p38 signaling for GM-CSF
Aoshiba et al., J Immunol 1999 : Granulocyte-macrophage CSF and anti-Fas Ab, which altered the rate of apoptosis, did not affect phosphorylation and activation of p38-MAPK