Gene interactions and pathways from curated databases and text-mining

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HDAC3 — VDR

Text-mined interactions from Literome

Herdick et al., J Mol Biol 2000 : This study demonstrates that the interaction of the VDR with NCoR results in a preferential stabilization of the VDR in a non-agonistic conformation ( silent state ), whereas within a complex with SRC-1 VDR is in its agonistic conformation ( activated state )
Reinhardt et al., Arch Biochem Biophys 1989 (Osteosarcoma) : This up-regulation was associated with reduced 1,25- [ 3H]D3 catabolism. 1,25- [ 3H]D3 induced up-regulation of VDR typically peaked at 14 h and declined thereafter
Reinhardt et al., J Biol Chem 1989 (Breast Neoplasms) : This apparent reduction in the affinity of VDR for 1,25- ( OH ) 2D3 was due to degradation of free 1,25- ( OH ) 2 [ 3H]D3 which occurred during whole cell saturation assay