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HDAC3 — VDR
Text-mined interactions from Literome
Herdick et al., J Mol Biol 2000
:
This study demonstrates that the interaction of the VDR with
NCoR results in a preferential stabilization of the
VDR in a non-agonistic conformation ( silent state ), whereas within a complex with SRC-1 VDR is in its agonistic conformation ( activated state )
Reinhardt et al., Arch Biochem Biophys 1989
(Osteosarcoma) :
This up-regulation was associated with reduced 1,25- [ 3H]D3 catabolism. 1,25- [
3H]D3 induced up-regulation of
VDR typically peaked at 14 h and declined thereafter
Reinhardt et al., J Biol Chem 1989
(Breast Neoplasms) :
This apparent reduction in the affinity of
VDR for 1,25- ( OH ) 2D3 was
due to degradation of free 1,25- ( OH ) 2 [
3H]D3 which occurred during whole cell saturation assay