Gene interactions and pathways from curated databases and text-mining

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CASP2 — HIF1A

Text-mined interactions from Literome

Yoshida et al., J Neurooncol 2006 (Adenoma...) : Microarray analysis indicated that HIF1-alpha down-regulated caspase-10
Chang et al., Acta Pharmacol Sin 2007 (Arterial Occlusive Diseases...) : The hypoxia-inducible factor-1alpha ( HIF-1alpha ), activation of caspase-3 , and TNF-alpha mRNA transcription in ischemic regions were detected by immunoblotting and RT-PCR, respectively
Krieg et al., Photochem Photobiol Sci 2007 : Analysis of caspase-3 and -9 expression, the activation of HIF-1alpha , Bcl2, Cox2 and the phosphorylation of AKT reveals signal activation due to a PDT-stimulus in correlation with the positive controls
Toblli et al., Nephrology (Carlton) 2008 (Anemia, Iron-Deficiency...) : Furthermore, overproduction of HIF-1alpha and the activation of caspase-3 seem to be associated with iron deficiency and with inflammatory markers
Li et al., Neurol Res 2011 (Brain Ischemia) : 2ME2 may decrease the HIF-1-alpha expression, up-regulate the survivin expression, inhibit the expression of caspase-3 , and finally reduce apoptosis after GI