Gene interactions and pathways from curated databases and text-mining

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HMGB1 — IL13

Text-mined interactions from Literome

Taniguchi et al., Arthritis Rheum 2003 (Arthritis, Rheumatoid...) : SFMs expressed RAGE and released TNFalpha, interleukin-1beta (IL-1beta), and IL-6 upon stimulation with HMGB-1
Kamau et al., J Gen Virol 2009 : HMGB1 regulated tumour necrosis factor alpha, interleukin (IL)-6 , IL-8 and alpha interferon secretion in DENV infected DCs
Lynch et al., Am J Nephrol 2010 : HMGB-1 has also been observed as an extracellular secreted protein in serum of patients with sepsis and has putative intracellular signalling effects regulating the production of interleukin-1 and tumour necrosis factor in a number of inflammatory conditions
Carbone et al., Clin Cancer Res 2012 (Cell Transformation, Neoplastic...) : HMGB1 and Nalp3 induce proinflammatory responses and lead to interleukin-1ß and TNF-a secretion and NF-?B activity, thereby promoting cell survival and tumor growth
Weng et al., Shock 2012 (Acute Disease...) : Honokiol significantly reduced the increases in serum tumor necrosis factor-a, interleukin 1, and nitric oxide levels 3 h and serum high-mobility group box 1 24 h after acute pancreatitis induction