Cirrincione et al., J Cardiovasc Pharmacol 2006
(Body Weight...) :
Inhibition of HMG-CoA reductase does not attenuate the pronounced aortic constriction induced increases in the early expression of TGF-beta1 , C1, and FN in this model of acute pressure overload of the rat heart
Araújo et al., Biomed Pharmacother 2010
(Disease Models, Animal...) :
The inhibitory function of atorvastatin on multiple parameters of main components of inflammatory angiogenesis revealed in this study is clearly associated with the modulatory effects of HMG-CoA reductase on VEGF, TNF-alpha and TGF-beta1 production