Gene interactions and pathways from curated databases and text-mining

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HSPB1 — PIK3R1

Text-mined interactions from Literome

Suga et al., Arch Biochem Biophys 2005 (MAP Kinase Signaling System) : These results suggest that PI3K/Akt plays a part in the AVP induced phosphorylation of HSP27 , maybe independently of p38 MAP kinase, in aortic smooth muscle A10 cells
Takai et al., J Cell Biochem 2006 : These results suggest that PI3K/Akt plays a part in the sphingosine 1-phosphate stimulated induction of HSP27 , maybe independently of p38 MAP kinase, in osteoblasts
Lim et al., Int J Oncol 2010 (Necrosis) : In conclusion, these results indicate that PI3K dependent HSP27 and p53 induction and PI3K- and ERK1/2 dependent inhibition of the GD-induced increase in RIPA-insoluble HSP27 and p53 protein levels by heat play a key role ( s ) in heat shock mediated switch of GD-induced necrosis to apoptosis