Gene interactions and pathways from curated databases and text-mining

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ICAM1 — PIK3R1

Text-mined interactions from Literome

Arnold et al., J Immunol 2005 : The virus induced ICAM-1 up-regulation was dependent on protein kinase C and A, PI3K , and p38 MAPK activity
Amin et al., Blood 2006 : Antisense oligodeoxynucleotides ( ODNs ) and inhibitors of Src, PI3K , p38, and NFkappaB significantly reduced rhMIF induced MN VCAM-1 and ICAM-1 expression ( P < .05 )
Lin et al., J Cell Physiol 2007 (Lung Neoplasms) : We initially observed that IL-1beta induced ICAM-1 promoter activity was attenuated by the inhibitors of Src ( PP1 ), PDGFR ( AG1296 ), PI3-K ( LY294002 and wortmannin ), and Akt ( SH-5 ), revealed by reporter gene assay, Western blotting, and RT-PCR analyses ... The involvement of Src and PI3-K/Akt in IL-1beta induced ICAM-1 expression was significantly attenuated by transfection of A549 cells with dominant negative plasmids of Src, p85 and Akt, respectively
Zhang et al., Wei Sheng Yan Jiu 2008 : [ Involvement of EGF receptor and PI3K in ICAM-1 expression in human airway epithelial cells exposed to zinc sulfate ] ... The expression of ICAM-1 mRNA and protein and activation of epithelial growth factor receptor (EGFR) and PI3K was determined using PCR and immunoblotting
Park et al., Br J Pharmacol 2013 : A PI3K specific inhibitor ( LY294002 ), Akt inhibitor VIII ( Akti ) and NF-?B inhibitors ( Bay-11-7082 and MG-132 ) attenuated the induction of ICAM-1 by PGE2