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ICAM1 — PTGS2
Text-mined interactions from Literome
Yu et al., Hepatology 2006
(Choline Deficiency...) :
In conclusion, induction of
COX-2 occurs in association with NF-kappaB activation and upregulation of TNF-alpha, IL-6, and
ICAM-1 in MCD diet
induced steatohepatitis
Valcárcel et al., Journal of translational medicine 2008
(Colorectal Neoplasms...) :
More importantly, spheroid derived CT26 cells increased lymphocyte function associated antigen ( LFA ) -1-expressing cell fraction by 3-fold ; and soluble
intercellular adhesion molecule (ICAM)-1 , given to spheroid cultured CT26 cells, further increased VEGF secretion by 90 %, via cyclooxygenase
(COX)-2 dependent mechanism
Xu et al., Br J Pharmacol 2009
(Arteritis...) :
In these rats, blood was in a hypercoagulable state ; plasma urocortin, prostaglandin E ( 2 ) and soluble
intercellular adhesion molecule-1 levels were elevated ; and the expression of urocortin, CRF ( 1 ) and CRF ( 1alpha ) -receptors,
COX-2 and ICAM-1 in rat femoral arteries were markedly
increased
Arteta et al., Hepatology 2010
(Carcinoma...) :
CONCLUSION
: ICAM-1 induced tumor
COX-2 decreased antitumor activity during hepatic metastasis through IL-1 induced ManR
Yang et al., J Biol Chem 2010
(Mouth Neoplasms) :
We found that overexpression of
COX-2 or exogenous PGE ( 2 )
increased migration and
intercellular adhesion molecule 1 (ICAM)-1 expression in human oral cancer cells
Yoon et al., PloS one 2011
(Graves Disease...) :
Quercetin significantly attenuated intercellular adhesion molecule-1 ( ICAM-1 ), interleukin (IL) -6, IL-8, and cyclooxygenase
(COX) -2 mRNA expression, and
inhibited IL-1ß induced increases in
ICAM-1 , IL-6, and IL-8 mRNA
Wu et al., Journal of neuroinflammation 2012
(Disease Models, Animal...) :
Neuroinflammation in RVLM was also associated with a
COX-2 dependent downregulation of endothelial nitric oxide synthase and an upregulation of
intercellular adhesion molecule-1
Bishop-Bailey et al., Biochem Biophys Res Commun 1998
:
Cyclo-oxygenase-2 regulates inducible
ICAM-1 and VCAM-1 expression in human vascular smooth muscle cells