Gene interactions and pathways from curated databases and text-mining

◀ Back to IL1B

IFI44 — IL1B

Text-mined interactions from Literome

Jiang et al., Hypertension 2000 (MAP Kinase Signaling System) : Interleukin-1beta activated p44/42 MAPK, and this activation was enhanced in the presence of N-acetyl-L-cysteine
Saijonmaa et al., J Vasc Res 2001 : TNF-alpha and IL-1beta activated p44/42 and p38 mitogen activated protein kinases ( MAPKs ) in HUVECs ; this was inhibited by the specific inhibitors of these kinases, PD98059 and SB202190, respectively
Hirafuji et al., Br J Pharmacol 2002 : IL-1beta increased the phosphorylation of p44/42 MAPK, while it did not apparently increase the phosphorylation of p38 MAPK ... DHA significantly potentiated the IL-1beta induced phosphorylation of p44/42 MAPK, while it had no significant effect on the phosphorylation of p38 MAPK
Vela et al., Mol Cell Neurosci 2002 : Regarding intracellular signaling, IL-1beta activated the p38 mitogen activated protein kinase ( MAPK ) but not the p42/p44 MAPK and, when combined with growth factors, intensified p38 activation but inhibited the growth-factor induced p42/p44 activation
Yang et al., Life Sci 2002 : Sphondin ( 50 microM ) did not affect the IL-1beta induced activations of p44/42 MAPK, p38 MAPK, and JNK
Bamba et al., Am J Physiol Gastrointest Liver Physiol 2003 : IL-1beta and TGF-beta1 induced an activation of ERK p42/44 and p38 MAP kinases, and the MAP kinase inhibitors ( SB-202190, PD-98059, and U-0216 ) significantly reduced the IL-1beta- and TGF-beta1 induced IL-11 secretion
Lin et al., J Biomed Sci 2004 : This hypothesis was further supported by the transient activation of p42/p44 and p38 MAPKs induced by IL-1beta
Lee et al., World J Gastroenterol 2006 (MAP Kinase Signaling System) : IL-1beta activates p44/42 and p38 mitogen activated protein kinases via different pathways in cat esophageal smooth muscle cells ... Phosphokinase C ( PKC ) was found to play a mediating role in the IL-1beta induced p44/42 MAP kinase activity ... Based on these results, IL-1beta induced p44/42 MAP kinase activation is mediated by the Gi protein, tyrosine kinase, phospholipase C (PLC) and PKC
Kesherwani et al., Cytokine 2007 : Quantitative role of p42/44 and p38 in the production and regulation of cytokines TNF-alpha, IL-1beta and IL-12 by murine peritoneal macrophages in vitro by concanavalin A ... In the present study the quantitative role of p42/44 and p38 in the production of TNF-alpha, IL-1beta and IL-12 by murine peritoneal macrophages, in vitro, on treatment with Concanavalin A ( ConA ) has been investigated ... The expression of TNF-alpha, IL-1beta and IL-12 was down regulated in the presence of PD98059 and SB202190 in a dose dependent manner, suggesting the involvement of p42/44 and p38 in ConA induced production of TNF-alpha, IL-1beta and IL-12 by macrophages
Sodhi et al., Glycoconj J 2007 : Pharmacological inhibitor of tyrosine kinase, PI3 kinase, protein kinase C, p42/44 , p38, JNK and intracellular calcium immobilizing agent down regulated the WGA induced expression of cytokines TNF-alpha, IL-1beta , IL-12 and IFN-gamma
Sheng et al., J Neuroimmune Pharmacol 2009 (MAP Kinase Signaling System) : IL-1beta triggered the activation of p38 and ERK1/2 ( p44/42) MAP kinase (MAPK) signaling pathways, but WIN55,212-2 mainly inhibited p38 MAPK phosphorylation