Dey et al., Biochim Biophys Acta 2000
:
In contrast to CSF-1, IFNgamma neither induces D1-Cdk4 complex formation and Rb hyperphosphorylation nor interferes with CSF-1 stimulated D1-Cdk4 interaction and Rb phosphorylation, while it completely blocks CSF-1 stimulated cell proliferation
Mandal et al., Oncogene 1998
:
The observed IFN-gamma mediated inhibition of CDK-2 and CDK-4 kinase activity was due to enhanced interactions with p21WAF1 and p27Kip1, respectively