Gene interactions and pathways from curated databases and text-mining

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IL18 — IRAK4

Text-mined interactions from Literome

Vidal-Vanaclocha et al., Proc Natl Acad Sci U S A 2000 (Liver Neoplasms...) : Exogenous IL-18 added to HSE also increased the number of adhering melanoma cells ; however, this was not affected by IL-1 receptor blockade or TNF neutralization but rather by anti-VCAM-1
Jabłońska et al., Arch Immunol Ther Exp (Warsz) 2002 : In the present study we investigated the effect of interleukin 18 (IL-18) on the production of IL-1beta and soluble IL-1 receptor II ( sIL-1RII ) by human neutrophils
Suzuki et al., J Immunol 2003 : Because TLR/IL-1R/plant R-containing receptors mediate signal transduction in a similar fashion, we investigated the role of IRAK-4 in IL-18R signaling
Kim et al., J Biol Chem 2005 (Inflammation) : Importantly, endogenous mPLK/IRAK was activated in response to TNF-alpha or interleukin 1 treatment of primary adipose cells