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CD40LG — IL5
Text-mined interactions from Literome
McDowell et al., Infect Immun 2002
:
Leishmania priming of human dendritic cells for
CD40 ligand induced
interleukin-12p70 secretion is strain and species dependent
Möttönen et al., Arthritis Res 2002
(Arthritis, Rheumatoid) :
Regulation of
CD154 induced
interleukin-12 production in synovial fluid macrophages
Wagner et al., Arterioscler Thromb Vasc Biol 2002
:
One consequence of this statin dependent downregulation of CD40 expression was a decrease in
CD40 ligand induced endothelial
interleukin-12 expression
Loskog et al., Clin Cancer Res 2005
(Carcinoma...) :
CD40L stimulation of dendritic cells
induces interleukin-12 expression that drives Th1 type of immune responses with activation of cytotoxic T cells
Bose et al., Hum Immunol 2007
(Carcinoma, Squamous Cell...) :
Natural killer cell mediated cytotoxicity of tumor cells initiated by neem leaf preparation is associated with
CD40-CD40L mediated endogenous production of
interleukin-12
Jenkins et al., J Immunol 2008
(Schistosomiasis mansoni) :
In this respect, optimal production of
IL-5 , IL-10, and IL-13 was
dependent upon
CD154 expression by both CD4 ( + ) T cells and non-lymphoid cells
Grabstein et al., J Immunol 1993
:
The induction of polyclonal Ig secretion by the recombinant
CD40 ligand required IL-4 and
IL-5 although optimal Ag-specific antibody formation required IL-2
Maliszewski et al., Eur J Immunol 1993
:
IL-4 was a potent co-stimulator of IgE and IgG1 in the presence of
CD40 ligand , and
IL-5 acted synergistically with IL-4 in these responses as well as in IgM and IgG3 production
Kennedy et al., Eur J Immunol 1996
:
CD40/CD40 ligand interactions are
required for T cell dependent production of
interleukin-12 by mouse macrophages
Peng et al., Eur J Immunol 1996
:
In this study we demonstrate that upon stimulation of human peripheral blood T cells through the T cell receptor (TCR)/CD3 complex,
CD40/CD40L interaction strongly
enhances the production of Th1 cytokines such as interleukin (IL)-2 and interferon (IFN)-gamma and Th2 cytokines such as IL-4,
IL-5 and IL-10 by a direct effect on T cells