Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Jenkins et al., Exp Hematol 2002 (Thrombocytopenia) : Hematopoietic abnormalities in mice deficient in gp130 mediated STAT signaling
Chen et al., J Virol 2006 : Human herpesvirus 8 interleukin-6 ( vIL-6 ) displays 25 % amino acid identity with human IL-6 ( hIL-6 ) and shares an overall four-helix-bundle structure and gp130 mediated STAT/mitogen activated protein kinase signaling with its cellular counterpart
Dierssen et al., J Biol Chem 2008 (Acute-Phase Reaction...) : Here we generated mice either defective ( Delta ) in hepatocyte-specific gp130 dependent Ras or STAT activation to define their role during liver regeneration
Kroy et al., PloS one 2012 : Differential role of gp130 dependent STAT and Ras signalling for haematopoiesis following bone-marrow transplantation ... Conditional gp130 knockout and knockin mice were used to delete gp130 expression ( gp130 ( dMx ) ), or to selectively disrupt gp130 dependent Ras ( gp130 ( dMxRas ) ) or STAT signalling ( gp130 ( dMxSTAT ) ) in BM cells