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CNR2 — IL8

Pathways - manually collected, often from reviews:

• Reactome Reaction: CNR2 → IL8 (reaction) Lambert et al., Science signaling 2008, Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Takami et al., Brain Res Mol Brain Res 1994

Text-mined interactions from Literome

Jbilo et al., FEBS Lett 1999 : Stimulation of peripheral cannabinoid receptor CB2 induces MCP-1 and IL-8 gene expression in human promyelocytic cell line HL60
Gkoumassi et al., Naunyn Schmiedebergs Arch Pharmacol 2009 : In human bronchial epithelial ( 16HBE14o ( - ) ) cells, CB(1) and CB(2) cannabinoid receptors are present, and their activation by the endocannabinoid virodhamine and the synthetic non-selective receptor agonist CP55,940 inhibits adenylyl cyclase and cellular interleukin-8 release