Gene interactions and pathways from curated databases and text-mining

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GAL — IL8

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Dallos et al., Neuropeptides 2006 (Inflammation) : The aims of this study were a systematic investigation of the effects of the neuropeptides substance P ( SP ), calcitonin gene related peptide (CGRP), vasoactive intestinal polypeptide (VIP) and galanin (GAL) on the inflammatory cytokine production ( IL-1alpha, IL-8 and TNF-alpha ) of the keratinocytes, and a study of their role in the production and secretion of nerve growth factor (NGF) and its precursor molecule ( proNGF )
Groux-Degroote et al., Biochem J 2008 (Cystic Fibrosis) : In the present study, we show that incubation of macroscopically healthy fragments of human bronchial mucosa with IL-6 ( interleukin-6 ) or IL-8 results in a significant increase in the expression of alpha1,3/4-fucosyltransferases [ FUT11 ( fucosyltransferase 11 gene ) and FUT3 ], alpha2-6- and alpha2,3-sialyltransferases [ST3GAL6 ( alpha2,3-sialyltransferase 6 gene ) and ST6GAL2 ( alpha2,6-sialyltransferase 2 gene ) ] and GlcNAc-6-O-sulfotransferases [ CHST4 ( carbohydrate sulfotransferase 4 gene ) and CHST6 ] mRNA