Gene interactions and pathways from curated databases and text-mining

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IL8 — PRKAG1

Text-mined interactions from Literome

Giri et al., J Neurosci 2004 (Inflammation) : A pharmacological activator of AMPK , 5-amino-4-imidazole carboxamide riboside ( AICAR ) inhibited lipopolysaccharide (LPS) induced expression of proinflammatory cytokines ( tumor necrosis factor alpha, interleukin-1beta , and interleukin-6 ) and inducible nitric oxide synthase in primary rat astrocytes, microglia, and peritoneal macrophages
Tang et al., Free Radic Biol Med 2011 (Pneumonia) : Inhibition of NADPH oxidase activation by apocynin or siRNA targeting p47(phox) ( a subunit of NADPH oxidase ) attenuated the increased intracellular ROS level, AMPK activation, and IL-8 induction ... Removal of intracellular ROS by N-acetylcysteine reduced the AMPK activation and IL-8 induction
Fitzgerald et al., PloS one 2012 (Carcinoma, Renal Cell...) : Finally, we have characterized that enhanced levels of IL-6 and IL-8 result in RCC cell invasion and that activation of AMPK reduces Nox4 expression, IL-6 and IL-8 production, and RCC cell invasion