Ehlting et al., J Biol Chem 2011
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Further analysis of downstream signaling events involved in the transcriptional regulation of IFNß gene expression suggests that, in the absence of MK2, MK3 impairs interferon regulatory factor 3 protein expression and activation and inhibits nuclear translocation of p65 Bagchi et al., Cytokine 2013
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Furthermore, degradation of inhibitory kappa B ( I?B ) kinase ( Ikk ) suggested that I?Bß was the main activating kinase for IRF3 regulated NF-?B activation and phosphorylation of p65