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IRS4 — PIK3R1
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Hprd Interaction:
IRS4
—
PIK3R1
(in vivo)
Sano et al., J Biol Chem 2002
-
IRef Intact Interaction:
Complex of 81 proteins
(association, tandem affinity purification)
Pichlmair et al., Nature 2012
-
IRef Intact Interaction:
Complex of 43 proteins
(association, tandem affinity purification)
Pichlmair et al., Nature 2012
-
IRef Intact Interaction:
Complex of 18 proteins
(association, tandem affinity purification)
Pichlmair et al., Nature 2012
-
IRef Intact Interaction:
Complex of 111 proteins
(association, tandem affinity purification)
Pichlmair et al., Nature 2012
-
IRef Ophid Interaction:
IRS4
—
PIK3R1
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
-
STRING interaction:
PIK3R1
—
IRS4
(interaction, mapped from grid bind reactome kegg_pathways mint intact)
-
STRING interaction:
IRS4
—
PIK3R1
(interaction, mapped from grid bind reactome kegg_pathways mint intact)
Text-mined interactions from Literome
Villarreal et al., Mol Cell Biochem 2006
:
These results suggest that Ins and Ang II modulate
IRS-4 tyr-phosphorylation in a
PI3K dependent manner
Villarreal et al., Regul Pept 2010
:
Role of
IRS-4 in
PI3-K activation by insulin in HepG2 cells, modulation by Angiotensin II ... We report also Ins induced
PI3-K activation
mediated by
IRS-4