Ghislain et al., J Interferon Cytokine Res 2001
:
Regulated expression of type I interferon ( IFN ) -stimulated genes ( ISG ) requires the binding of the signal transducer and activator of transcription ( Stat ) complexes to enhancer elements located in the ISG promoters
Yin et al., J Virol 2009
:
However, inhibition of STAT phosphorylation by VEEV replicons was not correlated with inhibition of IFN stimulated gene ( ISG ) mRNA induction, yet ISG induction was inhibited when sP were present
Byrnes-Blake et al., J Interferon Cytokine Res 2012
(Hepatitis C, Chronic) :
However, STAT1 phosphorylation, MHC class 1 upregulation, and ISG induction in leukocytes only occurred with IFNa