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ITGAL — RUNX1

Text-mined interactions from Literome

Puig-Kröger et al., J Biol Chem 2000 : AML1B/CBFbeta transactivated the CD11a promoter, with AML1B/CBFbeta mediated transactivation being completely dependent on the integrity of the CD11a-110 element
Puig-Kröger et al., Blood 2003 (Leukemia, Myeloid) : RUNX/AML and C/EBP factors regulate CD11a integrin expression in myeloid cells through overlapping regulatory elements ... The relevance of the AML-110 element is underscored by the ability of AML-1/ETO to inhibit CD11a promoter activity, thus explaining the low CD11a/CD18 expression in t ( 8 ; 21 ) -containing myeloid leukemia cells