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IL10 — ITIH4

Text-mined interactions from Literome

Borghi et al., J Virol 1995 : Monoclonal antibodies to gp120 strongly inhibited recombinant gp120 induced IL-10 secretion by monocytes/macrophages
Shearer et al., Pediatr Res 1993 (HIV Infections) : Recent data suggest that multiple and independent immunosuppressive factors, including gp120 induced suppression and IL-10 , are responsible for the loss of TH function seen in HIV infected individuals before development of symptoms
Taoufik et al., Blood 1997 : Human immunodeficiency virus gp120 inhibits interleukin-12 secretion by human monocytes : an indirect interleukin-10 mediated effect ... We showed that in human monocyte cultures, HIV-gp120 induces a significant IL-10 synthesis, which in turn inhibits IL-12 subunits mRNA accumulation and protein secretion after SAC-activation